偏头痛的历史和COVID-19的风险:一个队列研究
Pamela M Rist1, Julie E Buring1, JoAnn E Manson1
1Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Mass.
The American journal of medicine
|August 20, 2023
概括
偏头痛史并没有显著增加老年妇女的COVID-19风险. 这项研究发现偏头痛和发展2019年新冠肺炎疾病 (COVID-19) 之间没有强烈的联系.
科学领域:
- 流行病学 流行病学
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 偏头痛和头痛是COVID-19的公认症状.
- 预先存在的偏头痛和感染COVID-19的风险之间的关系仍未得到充分研究.
研究的目的:
- 调查偏头痛病史与患COVID-19的风险之间的关联.
- 为了确定偏头痛患者是否对SARS-CoV-2感染的易感性增加.
主要方法:
- 来自妇女健康研究的16492名妇女的前性队列研究.
- 2020年之前医生诊断的偏头痛病史.
- 基于阳性测试,医疗保健提供者诊断或住院治疗的COVID-19分类.
- 逻辑回归与反向概率权重用于分析.
主要成果:
- 4759名女性 (28.9%) 报告有过偏头痛的病史.
- 在偏头痛史和患COVID-19的风险之间没有发现显著的关联 (OR 1.08;95% CI,0.95-1.22).
- 对偏头痛亚型和COVID-19住院治疗的子组分析产生了类似的零结果.
结论:
- 偏头痛病史与老年妇女患COVID-19的风险增加无关.
- 这些发现表明,偏头痛不会对SARS-CoV-2感染产生明显的易感性.
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