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[皮状内皮病变的检测率和临床特征]

L Zhang¹, Y P Xiao², X Tao²

¹Cervical Disease Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.

Zhonghua fu chan ke za zhi

|August 20, 2023

概括

皮状内皮病变 (SIL) 的检测率约为3%,人类乳头瘤病毒 (HPV) 感染率高达92.7%. Vulvar SIL,特别是高度的SIL,通常与宫和阴道病变同时发生,HSIL的结肠镜精度较低.

科学领域:

妇科妇科医生妇科
在瘤学瘤学.
病理学病理学病理学

背景情况:

阴道状内皮损伤 (SIL) 是一种影响阴道的癌前疾病.
早期检测和准确的诊断对于防止 vulvar 癌症的进展至关重要.

研究的目的:

为了研究阴道SIL.的检测率和临床特征.
分析人类乳头瘤病毒 (HPV) 感染率,基因型和相关病变.

主要方法:

在被诊断患有 Vulvar Low-grade (LSIL) 和 High-grade (HSIL) SIL 的女性中,通过结肠镜导向活检进行了回顾性分析.
从2018年1月到2022年8月,包括HSIL与LSIL案件的1:1比率.
分析HPV感染,细胞学,镜印记和病变位置.

主要成果:

部SIL的检测率每年增加,平均为2.57%.
总体HPV感染率为92.7%,HSIL (96.0%) 的高于LSIL (89.5%). 在这两组中,HPV 16是最常见的基因型.
对HSIL的结肠镜精度明显低 (40.2%),而不是LSIL (81.7%). 同时出现的宫和阴道病变很常见 (57.3%),特别是在HSIL.

结论:

Vulvar SIL检测率约为3%,HPV患病率很高.
Vulvar HSIL 经常与子宫和阴道病变同时发生.
对于HSIL的低胆管镜精度需要彻底的部检查和检查可疑病变的活检.

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