相关实验视频

Updated: Jul 21, 2026

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
08:49

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

Published on: January 22, 2019

9.2K

探索潜在的Plasmodium激酶抑制剂:联合对接,MD和QSAR研究

Sèlonou Gautier Kankinou1, Muslum Yildiz2, Abdulkadir Kocak1

  • 1Department of Chemistry, Gebze Technical University, Kocaeli, Turkey.

Journal of biomolecular structure & dynamics
|August 21, 2023
PubMed
概括

研究人员通过对数以百万计的化合物进行查,确定了潜在的疟疾治疗方法,以对抗Plasmodium falciparum蛋白激酶. 两个真实和两个假设的化合物显示为疟疾药物发现的有效抑制剂的承诺.

关键词:
这是一种抗疟疾药物.在QSAR中使用QSAR.分子动态模拟的分子动态模拟.蛋白质激酶酶是一种蛋白质激酶.泰米诺托的相似性

更多相关视频

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases09:13

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases

Published on: November 22, 2024

1.4K
Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors10:29

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Published on: May 9, 2025

1.2K

相关概念视频

Antiprotozoal Agents01:21

Antiprotozoal Agents

Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...