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瓦尔萨坦纳米脂质复合物的配方,体外评估和优化,采用Box-Behnken设计

- Magdy I Mohamed1, - Hanaa A Mahmoud1, - Amir I Mohamed2

  • 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt.

Pakistan journal of pharmaceutical sciences
|August 21, 2023
PubMed
概括

瓦尔萨坦脂复合体 (VAL-PLC) 是为了提高药物的生物可用性而开发的. 优化的VAL-PLC显示了药物含量,颗粒大小和pH独立溶解的改善,这表明了沙坦输送的有希望的方法.

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Structure-Activity Relationships and Drug Design01:28

Structure-Activity Relationships and Drug Design

Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
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