在渐进的超核性麻中,视觉定位抑制热量尼斯塔格姆 - 与帕金森病的比较
Rie Naito1, Yuki Watanabe1, Akira Naito1
1Department of Neuro-Otology, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo, Japan.
Journal of vestibular research : equilibrium & orientation
|August 21, 2023
概括
视觉固定抑制 (VS) 障碍是区分渐进性上核麻 (PSP) 与帕金森病 (PD) 的关键指标. 这项研究强调了VS作为早期PSP的潜在诊断生物标志物.
科学领域:
- 神经科学是一个神经科学.
- 眼科医生 眼科 眼科
- 神经学 神经学
背景情况:
- 视觉固定抑制 (VS) 障碍在逐渐超核性麻 (PSP) 中没有得到充分证实.
- 区分早期的PSP与帕金森病 (PD) 可能是临床上具有挑战性的.
研究的目的:
- 评估卡路里尼斯塔格姆斯受损VS作为诊断标志物,以区分PSP与PD的有用性.
- 调查VS和其他眼运动功能的关系以及PSP中神经成像发现.
主要方法:
- 对26名PSP和26名PD患者的回顾性分析.
- 使用电子吸收术评估热量吸收器,水平追逐,动和光动学吸收器的VS.
- 与神经放射学发现的相关性.
主要成果:
- 中位数VS%在PSP患者中为0%,在PD患者中为50.0%,表明PSP显著受损.
- 即使在早期疾病阶段,PSP的VS损伤也很明显.
- 损伤的VS与PSP中的冲动速度和光运动性阴影相关,并与亚体内核缩或前叶低流相关.
结论:
- 视觉固定抑制 (VS) 可以作为一个有价值的生物标志物来区分PSP和PD.
- 连接大脑皮层和基底腺节的小脑网络可能在PSP中VS受损方面发挥作用.
更多相关视频
相关概念视频
Parkinson's Disease: Overview
596
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
596
Parkinson's Disease: Treatment
297
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
297
Glaucoma: Overview
621
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
621
Angle Closure Glaucoma: Treatment
560
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
560
Visual Agnosia
236
Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
236
Neural Regulation
39.5K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.5K


