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在口腔中的Streptococcus mutans作为威胁流产的风险因素
Hanna I Klimek1, Hanna Moczulska2, Piotr Sieroszewski3
1Department of Fetal Medicine and Gynecology, Medical University of Lodz, Poland, Poland. hanna.i.klimek@gmail.com.
Ginekologia polska
|August 21, 2023
概括
口腔流感菌 (Streptococcus mutans) 可能会增加孕妇可能流产的风险. 这项研究分析了162名女性的细菌殖民,发现那些怀孕威胁的女性的S. mutans水平更高.
科学领域:
- 微生物学 微生物学
- 产科 产科 产科 产科 产科
- 妇科 妇科医生 妇科
背景情况:
- 在怀孕期间,口腔和阴道生态系统的细菌殖民是至关重要的.
- 了解微生物的转变可能会为怀孕并发症提供洞察力.
研究的目的:
- 为了研究在孕妇的口腔和阴道生态系统的细菌殖民在头三个月.
- 识别与堕胎威胁相关的潜在微生物风险因素.
主要方法:
- 分析了162名孕妇的口腔和阴道抽样 (99名有堕胎威胁,63名健康).
- 聚合酶连锁反应 (PCR) 用于检测特定的细菌:突变性 estreptococcus,状肠杆菌,埃舍里希亚大肠杆菌,乳杆菌酸性菌,Prevotella中间,Gardnerella阴道菌和Streptococcus agalactiae.
主要成果:
- 与健康对照人群相比,有堕胎威胁的妇女的口腔中Streptococcus mutans的发病率明显高 (p=0.046).
- 在健康怀孕的女性的阴道微生物群中,Lactobacillus acidophilus明显更常见 (p=0.041).
结论:
- 口腔流感菌 (Streptococcus mutans) 可能成为可能导致堕胎的潜在危险因素.
- 需要进一步的研究来阐明特定的口腔细菌在怀孕早期结果中的作用.
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