在状细胞疾病中小儿整形外科手术的外科并发症
Daniel Lorenzana1, Crystal A Perkins, S Clifton Willimon
1Children's Healthcare of Atlanta Atlanta, GA.
Journal of pediatric orthopedics
|August 21, 2023
概括
患有状细胞疾病 (SCD) 的儿科患者在骨科手术后面临16%的并发症风险. 部手术和先前的急诊室访问显著增加了这种风险.
科学领域:
- 整形外科手术 整形外科手术
- 儿科血液学 儿科血液学
- 状细胞疾病管理管理
背景情况:
- 状细胞疾病 (SCD) 患者经历了由诸如感冒,缺氧,感染,脱水和压力等因素引发的血管闭塞,所有这些都是潜在的手术并发症.
- 在接受整形外科手术的儿科SCD患者的外科并发症需要确定预测因素.
研究的目的:
- 为了确定患有状细胞病的儿科患者进行骨科手术的术后并发症的预测因素.
主要方法:
- 2009-2019年期间接受了骨科手术的SCD儿科患者 (≤21岁) 的单中心回顾性审查.
- 数据包括患者病史,手术前干预 (补水,输血),实验室结果和手术细节.
- 主要结局:在30天内出现术后并发症,定义为急救诊所或住院.
主要成果:
- 分析了92名儿科SCD患者的118次手术;16%的患者经历了术后并发症.
- 部手术 (24%) 的并发症明显比其他部位 (9%) 更多.
- 之前四次或以上的急救诊所 (OR 5.7) 和手术前输血 (27%对5%) 与增加的并发症率有关.
结论:
- 儿科SCD患者在骨科手术后有16%的术后并发症风险.
- 部手术和经常去急救诊所的病史是并发症的重要危险因素.
- 手术前输血意外地与更高的并发症率有关,需要进一步调查.
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