在接受血液透析的患者中,由炎症和认知障碍产生的饮食模式之间的关系
Yan Zhuang1, Xinmei Wang2, Xuanrui Zhang1
1Medical School (School of Nursing), Nantong University, Nantong, Jiangsu, China.
Frontiers in nutrition
|August 21, 2023
概括
与高C反应蛋白 (CRP) 水平相关的特定饮食模式显著增加了血液透析患者认知障碍 (CI) 的风险. 这种模式涉及大量摄入大米,烈酒,水果,茶和咖啡.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 营养科学 营养科学
- 神经科学是一个神经科学.
背景情况:
- 炎症与血液透析 (HD) 患者的认知障碍 (CI) 有关.
- 影响HD患者炎症的饮食模式及其对CI的影响需要进一步调查.
研究的目的:
- 检查来自C-反应蛋白 (CRP) 和IL-6 (IL-6) 的饮食模式与HD患者的CI之间的关联.
主要方法:
- 通过食物频率问卷评估的饮食摄入量.
- 降低等级回归 (RRR) 使用IL-6和CRP识别了使用IL-6和CRP的饮食模式.
- 使用蒙特利尔认知评估 (北京版) 评估认知功能.
- 多变量逻辑回归分析了饮食模式和CI之间的关联.
主要成果:
- 在IL-6衍生的饮食模式和CI之间没有发现显著的关联.
- 与高CRP水平相关的饮食模式 (高米,烈酒,水果,茶,咖啡;低深色蔬菜,果汁) 显著增加了CI风险 (AOR 8.62).
- 在调整了许多混因素 (AOR 14.54) 之后,这种关联仍然很重要.
结论:
- 高CRP的饮食模式与血液透析患者的认知障碍风险增加有关.
- 特定的食物,如大米,烈酒,水果,茶和咖啡可能会导致这种风险.
- 需要进一步的研究来证实海鲜,甜饮料和酒精在HD患者的CI中的作用.
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