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社会认知和交互训练在精神分裂谱系障碍的门诊患者中的有效性:随机对照试验
Joanna M Fiszdon1,2, H Drew Dixon3, Charlie A Davidson4,5
1VA Connecticut Healthcare System, West Haven, CT, United States.
Frontiers in psychiatry
|August 21, 2023
概括
社会认知交互训练 (SCIT) 与等待列表对照相比,对精神分裂症患者的结果没有显著改善. 然而,较短的疾病持续时间预测了更好的治疗反应和自尊.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 神经科学是一个神经科学.
背景情况:
- 社会认知缺陷与精神分裂症中的功能障碍有关.
- 社会认知交互培训 (SCIT) 是一种以人工为基础的,以小组为基础的干预,旨在提高社会认知.
研究的目的:
- 评估SCIT在精神分裂症门诊患者中的疗效.
- 为了确定SCIT治疗效果的潜在调节者.
主要方法:
- 51名门诊患者被随机分配到SCIT或等候名单控制 (WLC).
- 评估包括社会认知,神经认知,自我报告,症状以及在基线和治疗后的功能.
主要成果:
- 与WLC相比,SCIT没有显著改善神经认知,社会认知,自我报告或症状.
- 一种趋势级效应有利于SCIT在人际关系和工具角色功能方面发挥作用.
- 基线神经认知没有缓解治疗效果.
- 较短的疾病持续时间与更好的训练后神经认知,自尊和症状和社会功能趋势水平的改善有关.
结论:
- 在这项试验中,SCIT没有显示出显著的疗效,这凸显了需要仔细选择结果测量措施的必要性.
- 需要进一步的研究来确定治疗主持人,以个性化对精神分裂症进行干预.
- 较短的疾病持续时间可能是精神分裂症治疗中神经认知和自尊的有利预后因素.
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