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Updated: Aug 7, 2026

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在小鼠模型中,Apolipoprotein E异型不会影响tau病理的跨突触传播

Caitlin Davies1, Jane Tulloch1, Ellie Yip1

  • 1Centre for Discovery Brain Sciences and UK Dementia Research Institute, The University of Edinburgh, Edinburgh, UK.

Brain and neuroscience advances
|August 21, 2023
PubMed
概括

阿波利波蛋白E4 (APOE4) 基因型是阿尔茨海默病的主要风险因素,它不会影响老鼠通过突触连接传播tau病理. 在这个模型中,tau的传播在不同的APOE基因型和年龄之间发生了类似的情况.

关键词:
这就是阿尔茨海默病的原因.亚脂蛋白 E 是一种非脂蛋白 E.阵列断层扫描 阵列断层扫描突触突触是指突触中的突触.知道的 知道的 知道的病症是一种病症.

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