一种稳定线性有限元素方法,用于异性质波态态动力学,并应用于心脏 perfusion
Namshad Thekkethil1, Simone Rossi2, Hao Gao1
1School of Mathematics and Statistics, University of Glasgow, Glasgow, UK.
Computer methods in applied mechanics and engineering
|August 21, 2023
概括
这项研究引入了一种新的有限元方法,用于非线性波波弹性,这对于理解心脏力学至关重要. 该方法准确地模拟了异型组织,揭示了其对左心室孔隙压力动态的重大影响.
科学领域:
- 计算力学是计算力学.
- 生物医学工程 生物医学工程
- 固体机械学 固体机械学
背景情况:
- 非线性多弹性对于模拟心脏等生物组织至关重要.
- 固体骨的异型性质显著影响着弹性行为.
- 需要准确的数值方法来实现复杂的波弹性配方的隐性时间集成.
研究的目的:
- 开发和验证一个稳定有限元方法,用于非线性弹性.
- 为了研究异型心肌性质对左心室 (LV) 孔隙压力动态的影响.
- 为了将孔隙压力变化与LV动态和增加质量的相关性.
主要方法:
- 为了稳定线性有限元素方法,采用了变化的多尺度方法.
- 实现了一个整合结构动力学和达西流的单体配方.
- 该方法使用超弹性和可弹性基准案例进行了验证,并在人类LV模型上进行了验证.
主要成果:
- 在电网收研究中,数值方法证明了二级准确性.
- 模拟显示,心肌异型性显著影响毛孔压力.
- 孔腔压力变化与LV动态相关,在心时达到顶峰.
结论:
- 拟议的方法准确地模拟非线性多弹性,特别是对于异型生物组织.
- 心肌无极性在心脏孔隙压力调节中起着至关重要的作用.
- 这些发现为左心室的生物力学提供了宝贵的见解.
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