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对肝细胞癌免疫疗法的图书统计研究

Zhiyi Li¹, Ying Zhang¹, Baipan Zhang¹

¹Cancer Center, The First Hospital of Jilin University, Changchun, China.

Frontiers in immunology

|August 21, 2023

概括

肝细胞癌 (HCC) 免疫疗法研究激增,中国的出版物领先. 未来的研究将集中在克服耐药性和通过新技术推进治疗.

科学领域:

在瘤学瘤学.
免疫学免疫学免疫学
图书统计学图书统计学

背景情况:

肝细胞癌 (HCC) 是一个主要的全球健康问题,由于肝脏的补偿机制,经常被诊断为晚.
目前的高级HCC治疗方法,包括化疗和向治疗,面临诸如耐药性,高成本和生活质量下降等挑战.
免疫疗法已成为晚期肝癌的革命性治疗方法,需要全面了解其研究领域.

研究的目的:

进行肝细胞癌 (HCC) 免疫治疗研究的文献分析.
阐明当前的情景,知识框架,研究焦点和HCC免疫疗法的新兴趋势.
提供对HCC免疫疗法的演变和未来方向的全面概述.

主要方法:

从1999年到2022年12月31日,使用科学引用指数扩展 (SCI-Expanded) 数据库进行了全面的文献搜索.
用Citespace和VOSviewer进行了对4,486篇论文和68,925篇参考文献的文献分析.
方法包括时间线分析,突发检测和并发分析,以评估研究热点,知识结构和进展.

主要成果:

在2021-2022年,HCC免疫疗法研究的出版量显著增加,超过了前十年.
中国在出版物方面领先 (50.08%),其次是美国和日本. 孙中山大学是最富有成效的机构.
研究热点已经转移,联合参考网络的检查显示,HCC免疫疗法的研究重点正在发展.

结论:

在过去的20年里,HCC免疫疗法研究显示出了显著的增长和演变.
未来的研究将集中在通过组合疗法克服耐药性,推进采用细胞免疫力 (例如,CAR-T) 和开发新的瘤标志物.
纳米技术,微生物学和基因编辑等技术的整合有望进一步增强HCC治疗方法.

关键词:

城市空间 (Citespace) 是一个城市空间.在HCC中,HCC是HCC,HCC是HCC.在VOSviewer中使用VOSviewer.圣经计量资料 (Bibliometric bibliometric bibliometric) 是指参考书目中的资料.肝细胞癌是肝细胞癌.免疫疗法免疫疗法肝癌肝癌是一种肝癌.

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