采取较少旅行的路线:在去COpAT的路上
Margaret Pertzborn1, Christina G Rivera2, Don Bambino Geno Tai3
1Department of Pharmacy, Mayo Clinic Health System, 1400 Bellinger Street, Eau Claire, WI 54702-1510, USA.
Therapeutic advances in infectious disease
|August 21, 2023
概括
使用口服药物的复杂门诊抗菌疗法 (COpAT) 是有效的,可与某些感染的静脉治疗相提并论. 本审查提出了对综合COpAT和OPAT计划的定义和实施策略.
科学领域:
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
- 临床实践 临床实践
背景情况:
- 抗菌疗法是现代医学的一个基石.
- 使用口服药物的复杂门诊抗菌疗法 (COpAT) 已经成为一个显著的进步.
- 口服COpAT证明了针对特定传染性综合征的门诊亲肠道抗菌疗法 (OPAT) 的非劣势性.
研究的目的:
- 审查有关口腔COpAT的当前文献.
- 为COpAT提出一个标准化的定义.
- 提供将COpAT整合到现有OPAT计划中的实用方法.
主要方法:
- 关于口服COpAT的现有研究的综合文献综述.
- 基于当前的证据,制定COpAT的拟议定义.
- 实施综合COpAT/OPAT计划的战略概要.
主要成果:
- 口服COPAT是一种可行的,有效的替代品OPAT对于某些感染.
- 当前文献中缺乏COpAT的明确定义.
- 医疗保健提供者需要实践实施指南.
结论:
- 综合的COpAT/OPAT计划可以加强门诊抗菌药物管理.
- 标准化的定义和监测对于成功实施COpAT至关重要.
- 这项工作为在临床实践中采用口服COpAT提供了框架.
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