开发一个知识图框架,以方便和授权植物研究中的翻译方法:谷物豆类的用例
Baptiste Imbert1, Jonathan Kreplak1, Raphaël-Gauthier Flores2,3
1Agroécologie, INRAE, Institut Agro, Univ. Bourgogne, Univ. Bourgogne Franche-Comté, Dijon, France.
Frontiers in artificial intelligence
|August 21, 2023
概括
本研究介绍了翻译研究的正统学驱动的知识基础框架 (Ortho_KB),这是一个新的图形数据库系统. Ortho_KB集成了多种植物基因组数据,使比较基因组学成为可能,加速了农业研究.
科学领域:
- 基因组学就是基因组学.
- 生物信息学是一种生物信息学.
- 植物科学 植物科学
背景情况:
- 基因型和测序成本已经下降,但关键的农业植物物种仍未得到充分研究.
- 对于许多物种,存在异质数据集,这阻碍了比较基因组学和知识转移.
- 整合不同的数据源和非协调的描述对翻译研究构成挑战.
研究的目的:
- 为植物研究开发一个整合和查询异质,多种类数据的框架.
- 通过利用跨物种保存的基因结构和功能来促进翻译性研究.
- 为农业研发创建一个直观而强大的平台.
主要方法:
- 开发了两个管道 (结构和功能) 来构建一个名为Ortho_KB的NoSQL图形数据库 (Neo4j) 框架.
- 结构管道建立了基于orthology的跨物种联系.
- 功能管道整合了定量特征位点 (QTL) 和RNA测序数据,在数据库中连接了算法.
主要成果:
- 成功填充了Ortho_KB,创建了OrthoLegKB,一个专门用于豆类的实例.
- 通过研究促进开花的基因的保护来证明框架的实用性.
- 查询使得能够识别控制物种间共同特征的基因.
结论:
- 正理学驱动的知识基础框架 (Ortho_KB) 为植物研究提供了一个直观而强大的平台.
- 开发的管道有效地整合了异质数据,支持比较基因组学.
- Ortho_KB促进了翻译性研究,加速了基因组知识在农业中的应用.
相关概念视频
Light Acquisition
8.5K
In order to produce glucose, plants need to capture sufficient light energy. Many modern plants have evolved leaves specialized for light acquisition. Leaves can be only millimeters in width or tens of meters wide, depending on the environment. Due to competition for sunlight, evolution has driven the evolution of increasingly larger leaves and taller plants, to avoid shading by their neighbors with contaminant elaboration of root architecture and mechanisms to transport water and nutrients.
8.5K
Transgenic Plants
7.3K
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
7.3K
Plant Breeding and Biotechnology
19.0K
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
19.0K
Improving Translational Accuracy
2.6K
2.6K
Key Elements for Plant Nutrition
18.8K
Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
18.8K
The Roles of Bacteria and Fungi in Plant Nutrition
36.1K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
36.1K


