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接触二手烟的风险和COVID-19感染的严重程度:多中心病例控制研究
Surekha Kishore1, Vandana Shah2, Om Prakash Bera3
1All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India.
Frontiers in public health
|August 21, 2023
概括
接触二手烟 (SHS) 显著增加了严重COVID-19疾病的风险. 这项研究发现,在家中或工作中独立使用SHS会增加COVID-19的严重程度,这突显了无烟环境的必要性.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 二手烟 (SHS) 是心血管和肺部疾病的已知危险因素.
- 以前的研究还没有完全探索SHS对COVID-19结果的影响.
- 了解SHS在COVID-19中的作用对于公共卫生干预至关重要.
研究的目的:
- 为了确定SHS暴露是否是COVID-19感染的独立风险因素.
- 评估SHS暴露与COVID-19严重程度,死亡率和并发症之间的关联.
- 调查SHS作为可能导致COVID-19不利结果的潜在贡献者.
主要方法:
- 在印度六个州进行了一项多中心病例控制研究.
- 严重的COVID-19病例与SHS暴露的轻度/中度COVID-19对照进行了比较.
- 邻居匹配,年龄和性别被用来进行比较;后勤回归分析了关联.
主要成果:
- 在家中暴露于SHS与严重COVID-19的几率高3.03倍.
- 在工作场所接触SHS的几率是严重COVID-19的2.19倍.
- COVID-19疫苗接种史,BMI和附带的厨房也与严重程度相关.
结论:
- 累积的二手烟暴露是严重的COVID-19的独立风险因素.
- 这些发现强调了减少SHS暴露的重要性,以减轻COVID-19的严重程度.
- 未来的研究应该包括生物标志物来量化SHS暴露及其影响.
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