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脊椎GA-68 合物吸收模仿肺部神经内分泌瘤转移

A Maman¹, S Gultekin²

¹Ataturk University, Faculty of Medicine - Nuclear Medicine, Ezurum, Turkey.

Acta endocrinologica (Bucharest, Romania : 2005)

|August 21, 2023

概括

一个分化良好的肺神经内分泌瘤 (NET) 通过手术成功治疗. 随访成像证实没有复发,脊椎病变被确定为假阳性,可能是血管瘤.

科学领域:

在瘤学瘤学.
放射学放射学是一门学科.
核医学就是核医学.

背景情况:

一名57岁的女性呈现出一个分化的肺神经内分泌瘤 (NET).
最初的分期显示了主要的肺损伤和可疑的脊椎损伤.
诊断成像包括CT,MRI,以及Ga-68 DOTATATE PET-CT. 这两种图像是最常见的.

研究的目的:

报告一个肺部神经内分泌瘤 (NET) 的病例,并随之发现一个偶然的脊椎发现.
为了评估Ga-68 DOTATATE PET-CT在分期NET中的诊断实用性.
评估患有肺 NET 和潜在的转移性脊椎病变的患者的管理和随访.

主要方法:

肺 NET 的诊断通过活检得到证实.
用计算机断层扫描 (CT),磁共振成像 (MRI) 和Ga-68 DOTATATE正子发射断层扫描-CT (PET-CT) 来进行分期.
患者接受了右肺叶切除术,随后进行了2年的随访,包括重复PET-CT.

主要成果:

肺部损伤显示高Ga-68DOTATATE吸收 (SUVmax: 80.61),与NET相一致.
第六个胸椎病变在最初的PET-CT上表现出轻度吸收 (SUVmax:3.70).
在CT和MRI上特有的"波尔卡点"和"corduroy布"成像发现表明良性脊椎血栓瘤,导致脊椎吸收被归类为假阳性. 手术后,患者仍然无症状,没有NET复发的证据.
随访PET-CT显示在第六脊椎中稳定,轻度吸收 (SUVmax:3.50) 没有增加大小,没有其他病理吸收.

结论:

肺部神经内分泌瘤 (NET) 需要全面的分期,以区分原发性疾病和偶然发现.
典型的成像特征可以帮助区分良性脊椎病变,如血管瘤,从转移,即使是轻微的辐射追踪器吸收.
初级肺 NET 的手术切除是有效的,仔细的随访证实了没有复发和脊椎发现的良性性质.

关键词:

Ga-68 DOTATATE 的吸收方式肺部 NET 肺部 NET 肺部 NET 在PET-CT中使用.图像检测的发现脊椎血瘤是一种脊椎血瘤.

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