手和脚的小骨的巨细胞瘤
Rahul Patel1, Rahul Parmar1, Srishty Agarwal2
1Orthopedics and Traumatology, New Civil Hospital, Surat, IND.
Cureus
|August 21, 2023
概括
巨细胞瘤 (GCTs) 很少影响手和脚,通常是在晚期出现的. 积极的治疗对于保护四肢和最大限度地降低复发风险至关重要,特别是手部GCT.
科学领域:
- 整形瘤学 整形瘤学
- 骨病理学 骨病理学
背景情况:
- 巨细胞瘤 (GCTs) 通常在长骨中发现,但很少涉及手和脚的小骨.
- 由于非特异性临床症状,诊断可能具有挑战性,需要对其进行遗传病理学确认.
研究的目的:
- 分析临床表现,治疗和GCT在四肢小骨中的结果.
- 评估不同外科手术方法和新辅助在治疗这些罕见的GCT方面的疗效.
主要方法:
- 一项追溯研究,对16名患有本病学证实手或脚GCT的患者进行了追溯研究.
- 使用了放射性评估,坎帕纳奇分期和肌肉骨瘤学会 (MSTS) 评分.
- 患者接受了延长切 (用骨移植或水泥),宽切除或块切除的治疗,在所有情况下都使用了新辅助.
主要成果:
- 大多数患者 (62.5%) 处于二十多岁,大多数 (81.25%) 患有晚期疾病.
- 手和脚的参与发生在同等程度上 (1:1比).
- 在接受切和骨移植治疗的6.25%患者中观察到复发,需要进一步的手术干预 (广泛切除或截肢).
结论:
- 手和脚的巨细胞瘤需要一种积极的治疗方法,重点是保护四肢功能和降低复发风险.
- 手部的GCT似乎更具侵略性,需要定制的治疗策略.
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