临床医生报告的白风评估结果措施:一个范围审查
Nanja van Geel1, Jolien Duponselle1, Liesbeth Delbaere1
1Department of Dermatology, Ghent University Hospital, Ghent, Belgium.
概括
这次审查确定了14个临床医生报告的结果措施 (ClinROMs) 来评估白风的程度,再颜色和活性. 需要进一步的研究,以建立关于它们在临床试验和实践中的使用的共识.
科学领域:
- 皮肤病学 皮肤病学
- 临床试验方法论 临床试验方法论
- 结果测量 结果测量
背景情况:
- 临床医生报告的结果测量 (ClinROMs) 对于在临床研究和实践中评估白风至关重要.
- 现有的ClinROM评估了白风的程度,再发色和活动,但缺乏全面的概述.
研究的目的:
- 识别和描述所有关于白风的ClinROMs的入门出版物,并提供验证数据.
- 详细说明这些仪器的特性,预期用途,强度和局限性.
主要方法:
- 在PubMed,Embase和Cochrane图书馆 (CENTRAL) 进行了系统的文献搜索,截至2022年7月.
- 确定了10篇文章,描述了14个不同的ClinROM用于白风评估.
主要成果:
- 六个ClinROM测量疾病的程度/再颜色化 (例如,VASI,VES,VESplus,VESTA).
- 七个ClinROM评估疾病活动 (例如,VSAS,VDAS,VDIS).
- 确定了一个综合评分 (VETFa).
结论:
- 针对白风的程度,再发色和活动,确定了14个ClinROM.
- 选择ClinROM取决于研究问题和临床环境.
- 进一步研究有效性,可靠性,响应性以及对仪器选择的全球共识至关重要.
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