临床谱和印度儿童中乳病的呈现变化
Sadhna Bhasin Lal1, Vybhav Venkatesh1, Aradhana Aneja1
1Division of Paediatric Gastroenterology & Hepatology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
The Indian journal of medical research
|August 21, 2023
概括
儿童的乳病 (CD) 根据年龄呈现不同,年幼的儿童表现出经典症状,年长的儿童越来越多地表现出非经典形式. 这一趋势表明,这种质不耐受性疾病的诊断模式正在演变.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 免疫学 免疫学 免疫学
- 遗传学 遗传学 是一个
背景情况:
- 乳病 (CD) 是一种由质不耐受引起的免疫媒介疾病.
- 这项研究评估了北印度儿科CD的临床,血清和组织学概况.
- 它调查了两十年来CD呈现的变化趋势.
研究的目的:
- 评估印度儿童乳病的临床,血清学和组织学特征.
- 为了识别小儿乳病呈现的变化趋势.
- 分析母乳养时间与CD发病/诊断之间的相关性.
主要方法:
- 对2000年至2019年期间被诊断患有CD的891名儿童的临床数据的回顾性审查.
- 对人口统计信息,症状,相关的自身免疫性疾病,血清学,活检结果和坚持无质饮食的分析.
- 统计分析以确定疾病表现的相关性和趋势.
主要成果:
- 发病和诊断时的平均年龄分别为4.0±2.7岁和6.2±3.1岁.
- 常见的症状包括生长失速 (70%),腹痛 (64.2%),腹张 (61.2%),腹 (58.2%).
- 非古典性CD呈现在年龄较大的儿童 (>10岁) 和2010年后诊断的儿童中更为频繁,这表明趋势趋向于非典型形式.
结论:
- 儿童CD呈现随年龄而有很大变化,近年来转向非经典形式.
- 早期诊断和坚持无质饮食对于管理相关的自身免疫性疾病至关重要.
- 这项研究突出了北印度最大的儿科CD单中心队列,为疾病趋势提供了宝贵的见解.
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