角膜移植排斥的管理和预防
Sohini Mandal1, Prafulla K Maharana1, Luci Kaweri2
1Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Indian journal of ophthalmology
|August 21, 2023
概括
皮质类固醇可以控制角膜移植排斥 (CGR),而免疫调节剂可以帮助高风险病例. 这篇评论详细介绍了CGR的细节.
科学领域:
- 眼科医生 眼科 眼科
- 免疫学 免疫学 免疫学
背景情况:
- 角膜移植排斥 (CGR) 的管理主要涉及皮质类固醇.
- 免疫调节剂对于长期免疫抑制和高风险的角膜移植至关重要.
- 穿透性角质形成术 (PKP) 中的经典CGR标志可能在内皮角质形成术 (EK) 中不同.
研究的目的:
- 审查角膜移植排斥 (CGR) 的临床方面.
- 讨论角膜移植排斥 (CGR) 的管理策略.
主要方法:
- 审查关于角膜移植排斥现有文献.
- 对CGR的临床症状和管理方案的分析.
主要成果:
- 皮质类固醇是CGR发作的主要治疗方法.
- 免疫调节剂对于高风险移植和长期免疫抑制是必不可少的.
- 内皮角质整形 (EK) 可能呈现微妙或不存在的经典CGR迹象.
结论:
- 有效管理和预防CGR对于减少供体角膜需求至关重要.
- 了解CGR的临床表现和管理对于成功的角膜移植至关重要.
- 本综述综合了关于CGR临床方面和治疗的当前知识.
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