动脉样硬化评估基于单点指尖脉冲监测,使用可穿戴的电子传感器
Yi Huang1, Lingyu Zhao2, Minkun Cai2
1Department of Cardiology, Southern University of Science and Technology Hospital (SUSTech-Hospital), Shenzhen, 518071, China.
Advanced healthcare materials
|August 21, 2023
概括
一个新的灵活的电离式压力传感器可以单点测量心脏指尖脉冲波速度 (hfPWV) 以评估动脉样硬化. 这种可穿戴技术为传统临床方法提供了可靠和准确的替代方案.
科学领域:
- 生物医学工程 生物医学工程
- 心血管研究研究心血管研究
- 可穿戴技术可穿戴技术
背景情况:
- 动脉样硬化,其特点是动脉硬化和斑块积累,是导致心血管疾病如中风的主要原因.
- 目前对动脉样硬化的临床评估依赖于脉冲波速度 (PWV) 测量,通常需要庞大的设备和熟练的操作人员.
- 现有的可穿戴PWV传感器通常使用双点测量,容易受到环境干扰,限制了它们的实用性.
研究的目的:
- 开发一种新的,单点策略来测量心脏指尖脉冲波速度 (hfPWV) 使用灵活的离子电子压力传感器.
- 建立基于hfPWV的可靠模型来评估动脉样硬化.
- 为可穿戴动脉样硬化评估系统提供基础.
主要方法:
- 使用灵活的离子电子压力传感器,具有高压分辨率 (0.1Pa),用于稳定的指尖脉冲监测.
- 采用单点测量策略来捕捉指尖脉冲波的特征峰值.
- 提取了前进和反射的脉冲波,以计算hfPWV的时间差 using Hiroshi的方法.
主要成果:
- 离子传感器展示了高压分辨率和广泛的线性范围,使得精确的脉冲波捕获.
- 建立了一个基于hfPWV的动脉样硬化评估模型.
- 开发的模型的准确性与现有的临床标准相当,并且在临床上得到了验证.
结论:
- 使用灵活的离子电子传感器开发了一种可靠的单点技术,用于使用灵活的离子电子传感器测量hfPWV.
- 基于hfPWV的模型为动脉样硬化评估提供了临床有效和准确的方法.
- 这项技术有望整合到可穿戴式动脉样硬化评估系统中.
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