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Updated: Jul 18, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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设计,合成和评估新的西二醇尿酸衍生物作为抗瘤剂

Mohamed H Aboutaleb1,2, Nadia S El-Gohary1, Hazem A Ghabbour1

  • 1Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

Archiv der Pharmazie
|August 21, 2023
PubMed
概括

新型西米达二尿素衍生物对白血病细胞系表现出强烈的抗癌活性. 化合物7l表现出比索拉费尼布更高的疗效,诱导了亡并抑制了关键的与癌症相关的酶.

关键词:
这是一种抗瘤药物.诱导亡 诱导亡胺醇的使用方法分子对接的分子对接.多酶抑制剂的使用

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