目前的技术和模型用于评估环境污染物的发展毒性
Yan Jiang1, Stanley Aniagu2, Tao Chen3
1Suzhou Medical College, Soochow University; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Soochow University.
Journal of visualized experiments : JoVE
|August 21, 2023
概括
本研究审查了评估环境有毒物对水生和陆生生物的影响的方法. 斑马鱼幼虫,胚胎和单身蜜蜂被用来检测骨损失,DNA损伤,心脏毒性和农药效应.
科学领域:
- 环境毒理学环境毒理学
- 发展生物学 发展生物学
- 生态毒理学 生态毒理学
背景情况:
- 本系列文章强调了使用模型生物来评估环境有毒物质的影响.
- 讨论的技术包括阿利沙林红色染色用于斑马鱼幼虫的骨损失,斑马鱼胚胎的DNA损伤的免疫光,以及心脏毒性胚胎模型.
- 此外,还提出了对农药对单独蜜蜂幼虫的影响的评估.
相关概念视频
Types of Toxins
1.8K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
1.8K
Mutagenicity and Carcinogenicity
1.3K
Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for Research on Cancer (IARC) classifies agents into four groups based on their carcinogenic potential. Group 1 agents are known human carcinogens; group 2A agents are probably carcinogenic to humans; group 3 agents lack data to support their role in carcinogenesis; and group 4 includes agents for which data support that they are not likely to be...
1.3K


