植物性饮食模式和帕金森病:英国生物银行的前性分析
Anna Tresserra-Rimbau1,2,3, Alysha S Thompson1, Nicola Bondonno1,4,5
1The Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast, United Kingdom.
概括
健康的植物性饮食,富含蔬菜,坚果和茶,与降低患帕金森病 (PD) 的风险有关. 相反,不健康的植物性饮食与此英国生物银行研究中更高的PD风险有关.
科学领域:
- 营养流行病学 营养流行病学
- 神经退行性疾病 神经退行性疾病
- 公共卫生 公共卫生
背景情况:
- 植物性饮食与降低慢性疾病风险有关.
- 植物性饮食与帕金森病 (PD) 风险之间的关联以前是未知的.
研究的目的:
- 调查不同植物性饮食与PD发病率之间的关联.
- 利用来自英国大型生物银行队列的数据.
主要方法:
- 对126,283名英国生物库参与者的前性研究.
- 评估总体 (PDI),健康 (hPDI) 和不健康 (uPDI) 的植物性饮食指数.
- 使用考克斯回归来分析跨饮食指数四分位数和特定食物组的PD风险.
主要成果:
- 最高的hPDI和PDI四分位数显示PD风险降低 (22%和18%).
- 更高的UPDI与38%的PD风险增加有关.
- 增加蔬菜,坚果和茶的摄入量与较低的PD风险相关.
结论:
- 健康的植物性饮食,强调蔬菜,坚果和茶,与较低的PD风险有关.
- 饮食选择在调节PD风险方面发挥着重要作用,特别是在基因敏感的个体中.
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