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在Trypanosoma cruzi感染期间cGAS-STING通路的激活导致组织依赖的寄生虫控制

Natasha Perumal1,2, Brooke White1, Fernando Sanchez-Valdez1

  • 1Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA.

Journal of immunology (Baltimore, Md. : 1950)
|August 21, 2023
PubMed
概括

该cGAS-STING通路感知Trypanosoma cruzi感染,最初在入口部位促进寄生虫的生长. 然而,它后来限制了心脏中的寄生虫数量,这是慢性感染损伤的关键器官.

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