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开发最佳的虚拟选策略,以识别使用DockBox套件的新型通关式受体连接体

Jordane Preto1, Francesco Gentile2,3

  • 1Centre de Recherche en Cancérologie de Lyon, Université Claude Bernard Lyon 1, Lyon, France. jordane.preto@univ-lyon1.fr.

Methods in molecular biology (Clifton, N.J.)
|August 21, 2023
PubMed
概括

这项研究引入了使用DockBox进行基于结构的虚拟查的新协议,以发现新型Toll-like受体 (TLR) 配体. 这种方法有助于开发用于治疗炎症,癌症和自身免疫性疾病的调节器.

关键词:
化学图书馆 化学图书馆连接物发现 连接物发现分子对接是分子对接.小分子是小分子.收费类受体的收费类受体.虚拟选是一个虚拟的选.

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