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相关概念视频

Hormones and Bone Tissue01:17

Hormones and Bone Tissue

2.7K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.7K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

3.0K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.0K
Synthesis and Functions of Calcitonin00:51

Synthesis and Functions of Calcitonin

2.0K
Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
2.0K
Bone Cells and Tissue01:30

Bone Cells and Tissue

4.7K
Bones contain a relatively small number of cells entrenched in a matrix of organic and inorganic components. Although bone cells compose only a small amount of the bone volume, they are crucial to its function. Four types of cells are found within the bone tissue— osteoblasts, osteocytes, osteogenic cells, and osteoclasts.
Osteoblasts and Osteocytes
The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the...
4.7K
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

3.4K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.4K
Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

4.6K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
4.6K

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相关实验视频

Updated: Jul 18, 2025

Osteoclast Derivation from Mouse Bone Marrow
06:17

Osteoclast Derivation from Mouse Bone Marrow

Published on: November 6, 2014

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骨质素:一种多方面的骨衍生激素.

Gerard Karsenty1

  • 1Departments of Genetics and Development, Vagelos College of Physicians & Surgeons, Columbia University, New York, New York, USA;

Annual review of nutrition
|August 21, 2023
PubMed
概括

骨质素是一种来自骨的激素,会影响哺乳动物的能量代谢,男性生育能力和认知能力. 本综述探讨了它在骨结构之外的多样性作用.

科学领域:

  • 内分泌学 在内分泌学.
  • 代谢过程中的代谢.
  • 神经科学是一个神经科学.

背景情况:

  • 骨质素是一种来自骨的分泌分子.
  • 它在动物和灵长类动物中充当激素.
  • 骨质素会影响多种生理过程.

研究的目的:

  • 审查骨质卡尔辛的多样性功能.
  • 专注于骨质卡尔对能量代谢的调节.
  • 探索潜在的共同主题,将骨质素的功能联系起来.

主要方法:

  • 功能丧失的实验. 功能丧失的实验.
  • 功能获取实验. 功能获取的实验.
  • 文献综述,重点关注骨质卡尔的作用.

主要成果:

  • 骨素影响能量代谢,类固醇生成和神经递质生物合成.
  • 它影响男性生育能力,电解质平衡,认知能力,应激反应和运动能力.
  • 骨质素的功能可能与骨结构相关的共同底层主题.

结论:

  • 骨质卡尔是一种具有广泛作用的类荷尔蒙.
关键词:
骨头 骨头 骨头 骨头危险驱逐剂是一种危险驱逐剂.能量代谢 能量代谢骨质卡尔辛是一种骨质卡尔辛.碳酸盐低碳化处理

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Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis
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Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis

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A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders
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A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders

Published on: June 8, 2014

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相关实验视频

Last Updated: Jul 18, 2025

Osteoclast Derivation from Mouse Bone Marrow
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Osteoclast Derivation from Mouse Bone Marrow

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Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis
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Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis

Published on: December 18, 2019

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A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders
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A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders

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  • 它的作用超越能量代谢,包括生殖和神经功能.
  • 一个统一的原则可能将骨质素的系统功能与其骨起源联系起来.