人类卵巢组织和卵泡液中的环境黑碳颗粒
Eva Bongaerts1, Katariina Mamia2, Ilmatar Rooda2
1Centre for Environmental Sciences, Hasselt University, 3590 Hasselt, Belgium.
Environment international
|August 21, 2023
概括
在人类的卵巢和卵泡液中发现了环境空气污染颗粒,特别是黑碳. 这一发现突出了一个潜在的机制,将空气污染与女性生育能力下降以及对卵细胞质量的影响联系起来.
科学领域:
- 生殖生物学 生殖生物学
- 环境健康科学 环境健康科学
- 毒理学 毒理学 毒理学
背景情况:
- 越来越多的证据将环境空气污染暴露与女性生育能力下降联系在一起.
- 空气污染颗粒的转移到女性生殖器官仍然没有被调查.
- 了解粒子转移对于评估生殖毒性风险至关重要.
研究的目的:
- 调查人类卵巢组织和卵泡液中环境黑碳颗粒的存在.
- 为了确定空气污染颗粒是否可以到达卵巢储备和卵细胞.
主要方法:
- 来自20名接受辅助生殖技术的妇女的卵泡液分析.
- 查了来自5个个体的成年人类卵巢组织样本.
- 黑碳颗粒的检测使用femtosecond脉冲激光诱导的白光生成.
主要成果:
- 在所有分析的毛囊液样本 (n=20) 中检测到黑碳颗粒.
- 在所有分析的卵巢组织样本 (n=5) 中发现了黑碳颗粒.
- 证实了环境空气污染颗粒的转移到卵巢和卵泡液中.
结论:
- 环境中的黑碳颗粒可以到达人类的卵巢和卵泡液.
- 这种直接暴露对卵巢储备和成熟卵细胞构成风险.
- 迫切需要澄清这种暴露对卵细胞质量,卵巢衰老和生育能力的影响.
相关概念视频
Oogenesis
63.8K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
63.8K
Ovarian Cycle
1.4K
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
1.4K


