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基于欧洲共识的基础细胞癌的诊断和治疗的跨学科指南-更新2023年

Ketty Peris¹, Maria Concetta Fargnoli², Roland Kaufmann³

¹Institute of Dermatology, Catholic University of the Sacred Heart, Rome, Italy; Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.

European journal of cancer (Oxford, England : 1990)

|August 21, 2023

概括

更新的欧洲指导方针为基底细胞癌 (BCC) 提供了新的分类,区分基底细胞癌 (BCC) 和基底细胞癌 (BCC).

科学领域:

皮肤病学和瘤学
癌症研究癌症研究
临床指南临床指南

背景情况:

基底细胞癌 (BCC) 是光皮人群中最常见的皮肤癌.
现有的治疗指南需要更新,以反映BCC管理的进步.
多学科专家的共识对于优化BCC诊断和治疗策略至关重要.

研究的目的:

为基础细胞癌 (BCC) 的诊断和治疗提出最新的欧洲建议.
为BCC引入新的临床分类系统,将其分为"易于治疗"和"难以治疗".
为各种BCC亚型和临床情景概述基于证据的治疗方法.

主要方法:

由欧洲专家组成的多学科小组制定最新的建议.
根据临床因素将BCC分为"易于治疗"和"难以治疗"的类别.
对诊断和治疗方式的当前证据的审查和综合.

主要成果:

诊断依赖于临床皮肤学特征,对于模两可的病例,强制性基因病理学.
对BCC的第一线治疗是彻底的外科切除;对于高风险或复发性BCC,建议进行微图控制的手术.
系统性疗法,如刺抑制剂 (vismodegib,sonidegib) 和免疫疗法 (cemiplimab),用于高级BCC,放射治疗和电化学疗法作为替代选择.

结论:

更新的指导方针为BCC提供了精细的分类和管理策略.
强调个性化治疗选择,考虑瘤特征和患者因素.
多学科讨论对于管理难以治疗的BCC至关重要,对高风险患者来说,长期随访至关重要.

关键词:

基底细胞癌瘤是一种基本细胞癌.分类分类分类分类.破坏性治疗是一种破坏性治疗.电化学疗法是一种电化学疗法.戈林综合征 (Gorlin综合征) 是一个严重的疾病.准则准则准则准则刺抑制剂刺抑制剂免疫治疗是一种免疫疗法.光动力学疗法是一种光动力学疗法.放射治疗疗法放射治疗疗法通过手术治疗治疗.局部治疗是局部治疗.

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