与不遵守土壤传播的虫社区大规模药物管理相关的看法
Kulandaipalayam Natarajan Sindhu1, Kumudha Aruldas1, Saravanakumar Puthupalayam Kaliappan1
1The Wellcome Trust Research Laboratory, Division of Gastrointestinal Sciences, Christian Medical College, Vellore, India.
The American journal of tropical medicine and hygiene
|August 21, 2023
概括
对土壤传播虫 (STHs) 进行大规模药物管理 (MDA) 的不良遵守与有关感染和药物安全的误解有关. 解决这些信念对于有效的STH控制计划至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 寄生虫学的寄生虫学
背景情况:
- 大规模药物管理 (MDA) 是控制土壤传播虫 (STHs) 的首要策略.
- 在MDA计划中非随机的合规性阻碍了成功的STH控制努力.
- 了解合规障碍对于优化公共卫生干预至关重要.
研究的目的:
- 调查非合规个体的看法,与合规的参与者相比,在一个全社区的MDA (cMDA) 的STHs.
- 确定与MDA计划不合规相关的关键因素.
- 为改善参与STH控制计划的战略提供信息.
主要方法:
- 在印度南部,在使用阿尔本达的cMDA期间进行了一项病例控制研究.
- 对不合规参与者的看法与合规参与者的看法进行了比较.
- 统计分析,包括赔率比率 (OR) 和95%置信区间 (CI),用于评估关联.
主要成果:
- 违规的主要原因包括缺乏感染 (97.4%),健康 (91%),害怕副作用 (12.8%),不喜欢药物 (10.3%).
- 违规与肠道的认识不足 (OR:9.63),认为cMDA仅适用于感染者 (OR:2.14) 和怀孕期间药物安全性 (OR:2.19) 或其他药物安全性 (OR:3.14) 的担忧有显著联系.
结论:
- 关于STH感染,药物必要性和安全性的误解是MDA计划不合规的重要驱动因素.
- 针对这些特定观念的有针对性的健康教育可以增强参与,提高STH控制的有效性.
- 优化MDA参与需要更深入地了解社区对除虫治疗的信仰和态度.
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