在没有先前存在心力衰竭的心房动患者中,左心室喷射小部分的实用性
Yasuhiro Hamatani1, Moritake Iguchi1, Kimihito Minami1
1Department of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
ESC heart failure
|August 21, 2023
概括
左下心室喷射分数 (LVEF) 显著增加心力衰竭 (HF) 住院的风险,心房动 (AF) 患者没有先前的HF. 这一发现有助于未来的风险分层和预防策略在AF中HF.
科学领域:
- 心脏病学 心脏病学
- 心脏衰竭研究研究
- 对心房的研究研究.
背景情况:
- 心房动 (AF) 是心力衰竭 (HF) 的已知危险因素.
- 在AF患者中预防HF,特别是那些没有先前存在HF的患者,需要进一步调查.
- 左心室喷射率 (LVEF) 是高频评估中的一个关键的回声心脏学参数.
研究的目的:
- 为了研究LVEF和发生的HF事件之间的联系,在患有AF但没有先前HF的患者中.
- 确定LVEF是否可以作为该人群中HF住院治疗的预后标志物.
主要方法:
- 分析Fushimi AF Registry,这是一个基于社区的前性调查.
- 包括2459名没有先前存在HF的AF患者,按LVEF分层 (轻度降低:40-49%,低于正常:40-59%,正常:≥60%).
- 多变量考克斯回归分析,以评估LVEF层与HF住院的关联,根据年龄,性别,AF类型和CHA2DS2-VASc得分进行调整.
主要成果:
- 较低的LVEF层 (40-49%和50-59%) 与正常LVEF (≥60%) 相比,独立地与HF住院风险显著增加有关.
- 轻微降低LVEF的高风险住院率为2.98 (95% CI: 1.99-4.45),低于正常LVEF的风险比为2.01 (95% CI: 1.44-2.82).
- 低于60%的LVEF与各个子组的高频率住院风险增加有显著的关联,表明增加的预后价值.
结论:
- 降低的LVEF是HF入院的重要独立预测因子在没有先前存在HF的AF患者中.
- LVEF测量为AF患者风险分层和预防发生的HF提供了有价值的预后信息.
- 这些发现支持在临床实践中使用LVEF来管理心脏衰竭风险的AF患者.
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