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Updated: Jul 18, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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TP53功能增益突变调节了非HPV相关的口腔状细胞癌中的免疫抑制微环境

Yewen Shi1,2, Xiaoyong Ren2, Shaolong Cao3

  • 1Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Journal for immunotherapy of cancer
|August 21, 2023
PubMed
概括

在口腔状细胞癌 (OSCC) 中获得功能TP53突变通过改变瘤免疫微环境 (TIME) 来促进瘤免疫逃避. 这导致生存率下降,突出显示TP53在癌症进展中的作用.

关键词:
细胞因子 细胞因子头部和部的新生瘤.免疫检查点抑制剂 免疫检查点抑制剂免疫疗法 免疫疗法瘤微环境是一个微环境.

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