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Updated: Jul 18, 2025

T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing
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T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing

Published on: January 12, 2021

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T细胞受体β变量基因多态性预测检查点封锁免疫疗法期间的免疫相关不良事件

Bettzy Stephen1, Joud Hajjar2, Shrutii Sarda3

  • 1Investigational Cancer Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Journal for immunotherapy of cancer
|August 21, 2023
PubMed
概括

识别T细胞受体β (TCRB) 基因多态可能预测接受免疫治疗的癌症患者的严重免疫相关不良事件 (irAEs). 某些TRBV单元型对这些严重的副作用具有保护作用.

关键词:
免疫检查点抑制剂 免疫检查点抑制剂翻译性的医学研究.

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