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Updated: Jul 18, 2025

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通过作为基因组组织者,NFIB促进了复制许可

Wenting Zhang1, Yue Wang1,2, Yongjie Liu3

  • 1Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, China.

Nature communications
|August 21, 2023
PubMed
概括

核因子I (NFIB) 蛋白组织染色质,促进DNA复制原始选择和复制前复制复合体 (pre-RC) 的组装. 过度表达NFIB导致癌症基因组不稳定性和耐药性.

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