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在DDT度与多样性和母乳养史之间的关系

Luis A Chávez-Almazán¹, Hugo A Saldarriaga-Noreña², Lorena Díaz-González³

¹Clinical and Epidemiological Innovation Unit of Guerrero, Ministry of Health of Guerrero, Av. Juan R. Escudero 158, Ciudad Renacimiento, Acapulco, 39715, México. chavez_79@hotmail.com.

Bulletin of environmental contamination and toxicology

|August 21, 2023

概括

原发性妇女在母乳中含有较高水平的有机农药,如二二三乙烯 (DDT) 和其代谢物二二二乙烯 (DDE). 母乳消费没有显著影响母亲的农药水平.

科学领域:

环境科学环境科学
毒理学毒理学毒理学
人类健康人类健康人类健康

背景情况:

有机农药 (OCP) 是持久性有机污染物 (POP),具有潜在的健康风险.
暴露是通过环境接触和饮食摄入而发生的.
DDT及其代谢物是广泛研究的OCPs.

研究的目的:

评估平等和母乳养对母乳中DDT和DDE度的影响.
量化来自墨西哥南部妇女的OCP水平.
探索孕产妇因素与OCP负担之间的潜在相关性.

主要方法:

气相色谱用于检测o,p'-DDT,p,p'-DDT和p,p'-DDE.
对墨西哥南部妇女的母乳样本进行了分析.
统计分析比较了基于平价和母乳养状态的OCP水平.

主要成果:

目标化合物的检测频率超过78%.
对于o,p'-DDT (0.010 mg/kg) 和p,p'-DDT (0.043 mg/kg) 的中位数度较低,但对于p,p'-DDE (0.672 mg/kg) 的中位数度较高.
与多夫妇妇女相比,初夫妇妇女的o,p'-DDT和p,p'-DDE水平显著更高 (p <0.05).
哺乳状态并没有显著改变母乳中的OCP水平.

结论:

均等性是影响母乳中DDT和DDE积累的重要因素.
在初婚妇女中,较高的DDT和DDE水平需要进一步研究暴露途径.
婴儿的母乳消费似乎没有影响母亲的OCP水平.

关键词:

母乳是母乳中的一种.这就是DDT DDT.墨西哥墨西哥墨西哥墨西哥有机类杀虫剂有机类杀虫剂持久性有机污染物持久性有机污染物

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