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Updated: Jul 18, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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TP53和p21 (CDKN1A) 多态性以及全身性红斑狼的风险

Jacyara Maria Brito Macedo1, Amanda Lima Silva1, Amanda Chaves Pinto1

  • 1Department of Biochemistry, State University of Rio de Janeiro - UERJ, Rio de Janeiro, Brazil.

Advances in rheumatology (London, England)
|August 22, 2023
PubMed
概括

在TP53和p21 (CDKN1A) 的遗传变异可能会影响系统性红斑狼 (SLE) 的风险. 特定的基因型显示出保护性或风险关联,并且在SLE患者中观察到与血清炎和神经障碍等临床特征的相互作用.

关键词:
遗传多形态的遗传多形态.系统性红血性狼 (Systemic lupus erythematosusus) 是一种全身性狼.这就是TP53的特点.在p2121中,

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