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Updated: Jul 18, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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被编程细胞死亡蛋白1诱导的过度甲状腺功能低下症的替代剂量抗体可能高于推剂量

Qian Zhang1, Yao Zhang2, Huijuan Zhu3

  • 1Department of Medical Oncology, Affiliated Hospital of Hebei University, Hebei Key Laboratory of Cancer Radiotherapy and Chemotherapy, Baoding, Hebei, 071000, China.

Endocrine, metabolic & immune disorders drug targets
|August 22, 2023
PubMed
概括

这项研究确定了通过编程细胞死亡蛋白1 (PD-1) 治疗诱导的甲状腺功能低下症的最佳levothyroxine替代剂量. 在PD-1相关的甲状腺功能低下症患者中,平均维持剂量为1.8μg/kg/天.

关键词:
甲状腺功能低下症 甲状腺功能低下症免疫检查点抑制剂 免疫检查点抑制剂与免疫相关的不良事件 (irAEs)编程细胞死亡蛋白1 抗体替代剂量. 替代剂量.甲状腺上腺炎症是什么

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