癌手术并发症的预测因素:国家注册研究
John Åkerlund1, Pernilla Sundqvist2, Börje Ljungberg3
1Department of Urology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Region Västra Götaland, Department of Urology, Sahlgrenska University Hospital, Gothenburg, Sweden. john.akerlund@me.com.
Scandinavian journal of urology
|August 22, 2023
概括
接受细胞癌 (RCC) 开放性手术的患者,与微创手术相比,经手术后主要并发症的几率是双倍的. 对并发症的关键预测因素包括美国麻醉学会 (ASA) 评分,瘤大小和功能.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术瘤学手术瘤学
- 腎臟病學 (nephrology) 是一種醫學.
背景情况:
- 全国范围的注册表为手术结果提供了有价值的现实数据.
- 细胞癌 (RCC) 的治疗包括各种手术和热切除菌.
- 评估术后并发症对于患者安全和治疗优化至关重要.
研究的目的:
- 评估RCC手术后手术后并发症的发生率和预测因素.
- 为了比较不同外科手术方法和RCC的热除之间的并发症率.
- 评估各种RCC治疗后的90天死亡率.
主要方法:
- 利用了瑞典国家癌登记 (2015-2019) 的数据.
- 分析了手术后并发症的频率和类型.
- 使用后勤回归来确定主要并发症 (Clavien-Dindo等级III-V) 和死亡率的预测因素.
主要成果:
- 整体并发症率为24%,其中8.7%是主要并发症.
- 开放式手术的并发症率是微创手术的两倍 (20%),而微创手术 (10%).
- 出血和感染是最常见的重大并发症;ASA得分,瘤直径和血清肌素预测了主要并发症.
结论:
- 流血和感染是RCC手术中的首要术后并发症.
- 最少侵入性手术与明显较少的重大并发症有关,而不是开放式手术.
- 主要并发症的预测因素包括ASA得分,瘤大小,功能和手术技术.
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