相关实验视频

Updated: Jul 18, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
10:10

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

Published on: March 31, 2019

8.4K

通过CRISPR-Cas9查,可以识别IRF1-SOCS1介导的负反循环,该循环限制了CXCL9的表达和抗瘤免疫力

Imran G House1, Emily B Derrick1, Kevin Sek1

  • 1Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC 3010, Australia.

Cell reports
|August 22, 2023
PubMed
概括

研究人员发现,准IRF1或SOCS1可以促进巨细胞中CXCL9的表达,从而增强抗瘤免疫力. 这一发现为改善免疫检查点阻塞疗法的有效性提供了新的策略.

关键词:
CP: 癌症 癌症 癌症克里斯普尔-Cas9是什么意思在Cxcl1010中使用.在Cxcl9这里是DCs DCs DCs.这里是 Irf1 的位置.这就是Socs1的意思.癌症 癌症 癌症 癌症 癌症免疫疗法 免疫疗法巨细胞是什么?巨细胞是什么?

更多相关视频

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes08:32

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes

Published on: May 23, 2025

278
Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies09:08

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies

Published on: June 2, 2021

1.9K

相关概念视频

CRISPR01:59

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
52.3K