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COVID-19大流行对源血捐献的影响

Mischa L Covington¹, Chesinta Voma², Sean R Stowell^1,2

¹Department of Pathology, Joint Program in Transfusion Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Journal of clinical apheresis

|August 22, 2023

概括

COVID-19显著减少了源血捐赠,影响了关键的血衍生药物 (PDMPs). 由于制造延迟,疫情后的短缺持续存在,突出显示了供应链的长期脆弱性.

科学领域:

医疗保健研究的研究.
免疫学免疫学免疫学
生物技术是生物技术.

背景情况:

随着COVID-19的流行,医疗保健服务,包括献血,也受到影响.
对源血捐献的具体影响,对于血衍生药物 (PDMPs) 至关重要,尚不清楚.
PDMP制造可能需要长达一年的时间,这可能会掩盖捐赠不足.

研究的目的:

确定COVID-19大流行对源血捐献的影响.
评估这些短缺的持续时间及其对PDMP可用性的影响.
识别等离子体供应链中的漏洞.

主要方法:

在COVID-19大流行期间分析源血捐献数据.
疫情前,疫情期间和恢复阶段的捐赠水平的比较.
捐赠趋势与PDMP生产时间表的相关性.

主要成果:

源血捐赠受到了COVID-19大流行不成比例的影响.
捐款短缺一直持续到2022年下半年.
尽管捐赠水平恢复,PDMP短缺预计将继续由于制造的交付时间.

结论:

随着COVID-19的流行,源血捐献发生了重大而持久的干扰.
由于PDMP的制造过程漫长,尽管捐赠率有所提高,但缺乏仍将持续.
该研究强调了等离子体采购的固有脆弱性,构成未来供应风险.

关键词:

IVIGIG IVIGIG 这是一个很好的例子.专辑蛋白 (albumin) 是一种血捐赠血捐赠血捐赠血衍生物药品血衍生物药品

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