脊椎大动脉化作为中风发展的危险因素:来自印度南部一个三级保健中心的病例对照研究
Kibballi M Adarsh1, H Pavithra2, Valiyapalathingal Abdul Rasheed1
1Radiodiagnosis and Medical Imaging, Yenepoya Medical College Hospital, Mangaluru, IND.
Cureus
|August 22, 2023
概括
脊动脉的化是中风的重要危险因素,特别是与糖尿病或高胆固醇相结合时. 较高的化程度表明中风风险增加.
科学领域:
- 神经学 神经学
- 血管医学 血管医学
- 放射学 放射学是一门学科.
背景情况:
- 在全球范围内,中风是导致死亡和残疾的主要原因,特别是在发展中国家.
- 已确定的中风风险因素包括高血压,糖尿病和脂质失调.
- 脊柱动脉中介和内密层的化是一种未被充分研究的潜在中风风险因素.
研究的目的:
- 为了评估脊椎大动脉化和中风之间的关联.
- 为了比较中风患者和对照者的化程度.
- 评估与化和其他因素相关的中风发展风险.
主要方法:
- 一个基于医院记录的病例控制研究.
- 包括150名中风患者 (病例) 和没有中风的年龄/性别匹配的对照.
- 通过计算机断层扫描成像评估脊髓关动脉化,以及其他中风风险因素.
主要成果:
- 与对照人群相比,右和左脊椎动脉中较高程度的化在中风病例中明显更为普遍 (aOR 6.61,p<0.001;aOR 2.32,p=0.032).
- 随着化度升高,糖尿病和高胆固醇水平 (aOR分别为9.98,2.32和4) 的增加,中风风险增加.
- 多种风险因素的存在进一步增加了中风风险.
结论:
- 脊动脉显著化是中风的主要危险因素.
- 在这些动脉中检测到中度至严重的化,即使在无症状的个体中,也应被视为中风的警告信号.
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