副甲状腺手术后腹腔透析患者的饥饿骨综合征
Heng Yeh1,2, Hsuan Yeh2,3, Chun-Cheng Chiang2,4
1Department of Emergency Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.
Endocrine connections
|August 22, 2023
概括
饥饿骨综合征 (HBS) 是副甲状腺切除术后的常见并发症,用于腹腔透析 (PD) 患者的二次性副甲状腺功能障碍症 (SHPT). 较低的手术前和较高的性酸酶和水平预测HBS的发展.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
背景情况:
- 二次性偏甲状腺症 (SHPT) 是末期病 (ESKD) 患者的常见并发症.
- 饥饿骨综合征 (HBS) 通常发生在偏甲状腺切除术后的透析患者中,患有耐火性SHPT.
- 关于腹透析 (PD) 患者的HBS风险因素和结果的数据有限.
研究的目的:
- 为了确定临床风险因素预测术后HBS在PD患者经过副甲状腺切除术.
- 为了评估HBS的结果在PD患者后副甲状腺切除术.
主要方法:
- 单中心回顾性研究66名PD患者,他们接受了为SHPT进行副甲状腺切除术 (2009-2019).
- 患者分为HBS (n=47) 和非HBS (n=19) 两种分层.
- 多变量逻辑回归分析以确定HBS的预测因子.
主要成果:
- 在帕西甲状腺切除术后的PD患者中,HBS发生在71.2%的患者中.
- 在HBS组中, postoperative nadir调整后的含量较低,性酸酶 (ALP) 的含量较高,的含量较高.
- HBS的预测因素包括手术前血清的降低,ALP的升高和水平的升高.
- 在HBS和非HBS组之间,甲状腺功能障碍症持续性/复发性或整体死亡率没有显著差异.
结论:
- 饥饿骨综合征是PD患者在SHPT的副甲状腺切除术后经常出现的并发症.
- 特定的手术前生化标志物可以预测HBS的发展.
- 在这种患者群体中,HBS的适当管理策略至关重要.
关键词:
饥饿骨综合征是什么意思过低血症 (hypocalcemia) 的情况副甲状腺切除术 (parathyroidectomy) 是一种切除甲状腺的方法.腹膜透析是指腹膜透析.二次性副甲状腺功能障碍症.更多相关视频
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