NONO::TFE3融合皮肤上皮质和状细胞瘤:一个病例系列
Sharlene Helene C See1, Shantel Olivares1, Maansi Kulkarni2
1Department of Dermatology, Section of Dermatopathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Journal of cutaneous pathology
|August 22, 2023
概括
我们发现了一种新的皮肤瘤与NONO::TFE3融合,展现出一个不寻常的SOX10和p63阳性免疫表型. 这些发现表明一种潜在的新亚型的周围血管上皮细胞瘤 (PEComa).
科学领域:
- 在瘤学瘤学.
- 皮肤病理学 皮肤病理学
- 分子病理学分子病理学
背景情况:
- 周周血管上皮质细胞瘤 (PEComas) 是一种罕见的介质细胞瘤.
- 在特定的细胞癌和皮肤外PEComa中识别了NONO::TFE3融合.
- 皮细胞瘤通常表达肌源性和黑色细胞标记物,而SOX10和p63的阳性以前没有报告.
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