与糖尿病人的阻塞性睡眠呼吸暂停相关的心血管疾病结果:系统性审查和元分析
Ganesh Bushi1, Bijaya Kumar Padhi1,2, Muhammed Shabil1
1Global Center for Evidence Synthesis, Chandigarh 160036, India.
Diseases (Basel, Switzerland)
|August 22, 2023
概括
在糖尿病患者中,阻塞性睡眠呼吸暂停 (OSA) 可能与心血管疾病 (CVD) 有关. 在糖尿病患者中早期发现和管理OSA可能有助于降低心血管疾病风险.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 睡眠医学 睡眠医学
背景情况:
- 糖尿病和阻塞性睡眠呼吸暂停 (OSA) 在病原和流行病学方面具有显著的重叠.
- 心血管疾病 (CVD) 是糖尿病人群的一个主要问题.
研究的目的:
- 系统地审查和确定在糖尿病患者中OSA和心血管疾病之间的关联.
主要方法:
- 在2023年7月15日,在多个数据库 (PubMed, EBSCO, Scopus, ProQuest, Web of Science) 进行了全面的文献搜索.
- 包括观察性研究报告的心血管疾病事件在糖尿病患者和没有OSA.
- 研究的质量使用纽卡斯尔-太华尺度来评估.
主要成果:
- 涉及17796名参与者的9项观察性研究符合纳入标准.
- 八项研究的元分析显示,在患有OSA的糖尿病患者中,心血管疾病的综合风险比 (RR) 为1.29 (95% CI = 0.91-1.83).
- 在包括的研究中观察到显著的异质性 (I2 = 91%).
结论:
- 在OSA和糖尿病之间存在潜在的关联,影响心血管疾病风险.
- 在糖尿病患者中早期发现和治疗OSA可能会减轻心血管疾病及其并发症的风险.
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