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Updated: Jul 18, 2025

Quantification of Breast Cancer Cell Invasiveness Using a Three-dimensional 3D Model
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Quantification of Breast Cancer Cell Invasiveness Using a Three-dimensional 3D Model

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机械生物细胞适应不断变化的微环境决定了癌症的侵入性:经过实验验证的有限元模型

Marina Tulchinsky1, Daphne Weihs1

  • 1Faculty of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa, Israel.

Journal of biomedical materials research. Part A
|August 22, 2023
PubMed
概括

癌细胞的侵入性是转移的关键因素,受瘤微环境的影响. 这项研究揭示了凝刚性和Poisson之间的关系.

关键词:
癌细胞的入侵 癌细胞的入侵细胞力学 细胞力学有限元素建模有限元素建模机械生物学 机械生物学

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In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
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