与过渡到严重精神疾病相关的因素
Sara Jalali1, Lu Liu1, JianLi Wang2,3
1Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
Canadian journal of psychiatry. Revue canadienne de psychiatrie
|August 22, 2023
概括
患有早期精神病症状和高度焦虑的女性年轻人更有可能患上严重精神疾病 (SMI). 这一发现有助于早期发现和干预风险青少年的策略.
科学领域:
- 精神病学是一个精神病学.
- 发展心理学 发展心理学
- 临床心理学 临床心理学
背景情况:
- 对于面临严重精神疾病风险的年轻人来说,早期干预至关重要.
- 关于风险青年中SMI发展的早期预测因素的知识有限.
研究的目的:
- 为了确定与精神病,双相情感障碍或严重/复发性主要抑郁症的发展相关的临床因素,在风险青年中.
主要方法:
- 一项对162名处于危险阶段的年轻人 (12至26岁) 的纵向研究.
- 在研究期间,31名参与者过渡到SMI.
- 考克斯回归分析比较了那些过渡的人与那些没有过渡的人的基线测量.
主要成果:
- 女性性别,减弱的精神病症状 (精神病风险症状量表 - SOPS) 和高的K-10痛苦量表得分预测了SMI过渡.
- 女人过渡的可能性是女性的2.77倍.
- 每个SOPS规模的增加与14%的过渡率增加相关;每一个K-10点的增加与7%的过渡率增加相关.
结论:
- 这些纵向发现突出了在风险青年中早期发现SMI的特定临床指标.
- 识别这些因素可以为有针对性的早期干预策略提供信息.
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