在接受手术内放射治疗的癌症患者的体内剂量测量
Anna Petoukhova1, Roland Snijder1, Thomas Vissers2
1Haaglanden Medical Centre , Department of Medical Physics, Leidschendam, The Netherlands.
Physics in medicine and biology
|August 22, 2023
概括
在体内剂量测量 (IVD) 对于手术内放射治疗 (IORT) 至关重要,特别是对于乳腺癌患者,以确保准确的剂量递送. 最近的进展集中在实时适应和超高剂量率 (FLASH) 放射治疗应用上.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
背景情况:
- 在体内剂量测量 (IVD) 对于验证外部束辐射疗法 (EBRT) 和手术内辐射疗法 (IORT) 的辐射剂量准确性至关重要.
- IORT,特别是低风险乳腺癌,涉及高单片剂量,增加精确剂量监测的重要性.
研究的目的:
- 总结最近的IVD方法的发展和临床应用,特别针对IORT.
- 突出挑战和未来方向,包括与实时治疗计划和超高剂量率 (FLASH) 放射治疗的整合.
主要方法:
- 审查目前适用于IORT的IVD技术.
- 讨论新兴技术,如手术内超声波和形光束CT用于实时IORT规划.
- 包括FLASH放射治疗的IVD考虑因素.
主要成果:
- 在IORT期间,IVD在注册输送剂量方面发挥着至关重要的作用,使治疗适应.
- 实时IORT规划系统正在开发中,增加了对准确IVD的需求.
- 用于FLASH放射治疗的IVD是一个有前途的领域,尽管尚未临床使用.
结论:
- IVD对于确保准确和适应性IORT至关重要,特别是在单片剂治疗中.
- 需要进一步开发综合治疗规划系统和IVD方法,以便广泛采用FLASH等先进的IORT技术.
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