在社区新生儿重症监护室减少抗生素使用:质量改善倡议
Harjinder P Singh1, Susan Wilkinson1, Shahid Kamran1
1Division of Neonatology, Pomona Valley Hospital Medical Center, Pomona, California.
American journal of perinatology
|August 22, 2023
概括
一项质量改善计划显著降低了新生儿重症监护室 (NICU) 的抗生素使用率. 这种多学科的方法使抗生素使用量减少了40%,改善了婴儿健康,并打击了抗生素耐药性.
科学领域:
- 新生儿医学 新生儿医学
- 传染性疾病 传染性疾病
- 提高质量 提高科学 提高质量
背景情况:
- 新生儿重症监护室 (NICU) 过度使用抗生素对婴儿健康构成风险,并导致抗生素耐药性.
- 基线抗生素使用率 (AUR) 为22%,在NICU中被确定为一个问题.
研究的目的:
- 实施多学科质量改善 (QI) 计划,以减少新生儿重症监护室 (NICU) 的抗生素使用率 (AUR).
- 具体目标是在5年内将AUR从22%降至17%.
主要方法:
- 在一个53张床位的3B级NICU中进行了为期5年的QI计划,其中包含了抗生素管理的核心元素.
- 策略包括制定基于证据的指导方针,每日管理轮次,败血症风险计算器和抗生素停止订单.
- 使用P图表的统计过程控制监控了季度AUR.
主要成果:
- 该计划实现了AUR持续下降,在研究期末达到13.18%.
- 这比基线AUR的22%下降了40%.
- 实施的变化包括基于证据的指导方针,每日管理轮次,败血症风险计算器和抗生素停止订单.
结论:
- 综合核心抗生素管理要素的多学科方法有效降低了NICU中的AUR.
- 这一举措证明了QI计划在优化脆弱新生儿群体抗生素使用方面的成功.
- 减少抗生素暴露对于预防伤害和对抗新生儿耐药性至关重要.
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