在一般实践中优化对常见感染的抗生素处方的知识支持:评估定期反的有效性,在咨询期间提供决策支持,并在集群随机试验 (BRIT2) 中进行同行比较 - 研究协议
Tjeerd van Staa1, Anita Sharma2, Victoria Palin3
1Centre for Health Informatics, The University of Manchester, Manchester, UK tjeerd.vanstaa@manchester.ac.uk.
BMJ open
|August 22, 2023
概括
这项研究调查了学习医疗保健系统 (LHS) 中的知识支持系统 (KSS) 是否可以改善初级保健中的抗生素处方. 目标是加强抗生素的使用,而不会增加常见感染的并发症风险.
科学领域:
- 初级护理研究初级护理研究
- 医疗信息学 医疗信息学
- 改善临床质量的改善.
背景情况:
- 抗生素耐药性需要在初级保健中改善处方实践.
- 学习医疗保健系统 (LHS) 为持续的质量改进提供了一个框架.
- 知识支持系统 (KSS) 可以帮助临床决策.
研究的目的:
- 评估KSS在LHS中的干预是否改善了对常见感染的抗生素处方.
- 为了确定KSS干预是否会增加并发症的风险.
- 评估数据驱动反对临床医生的处方行为的影响.
主要方法:
- 实用集群随机对照试验,涉及英格兰西北部的一般实践.
- 干预措施包括实践级反仪表板和集成到电子健康记录中的KSS.
- 分析大型医疗记录数据库,以告知仪表板和KSS内容.
主要成果:
- 主要结果是实践水平的抗生素处方率.
- 二次结果集中在患者安全和并发症风险上.
- 将对抗生素使用中的数据异质性进行表征.
结论:
- 这项研究旨在通过技术支持的质量改进提供关于优化抗生素处方的证据.
- 结果将为开发和实施有效的KSS和LHS模型提供信息.
- 传播包括同行评审的出版物和与临床医生和政策制定者的接触.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
2.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K
Combined Effects of Drugs: Synergism
4.0K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
4.0K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
15
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
15
Antibiotic Selection
54.7K
Overview
54.7K
Antimicrobial Effectiveness
48
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
48
Urine Studies II: Urine Culture and Sensitivity Test
54
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
54


