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预先知识对记忆检索过程中大脑激活和功能连接的影响
Dingrong Guo1, Haoyu Chen1, Lingwei Wang1
1School of Psychological and Cognitive Sciences, Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, 100871, China.
Scientific reports
|August 22, 2023
概括
之前的知识通过参与不同的大脑网络,显著影响记忆检索. 腹部中部前额叶皮层 (vmPFC) 和海马子区域显示基于先前知识水平的差异激活和连接.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 记忆研究 记忆研究
背景情况:
- 腹部中间前额叶皮层 (vmPFC) 参与了与模式相关的记忆.
- 海马子区域在检索与模式相关的记忆中的作用是有争议的.
- 预先知识 (PK) 如何调节记忆检索中的功能连接 (FC) 尚不清楚.
研究的目的:
- 研究海马子区域在与模式相关的记忆检索中的参与.
- 为了检查事先知识 (PK) 如何影响vmPFC,海马体和其他大脑区域之间的功能连接 (FC) 随着时间的推移在记忆检索过程中.
主要方法:
- 参与者从熟悉的 (高PK) 和不熟悉的 (低PK) 类别中学习信息.
- 在学习后的20分钟,1天和1周,在fMRI扫描仪中执行了识别任务.
- 基于先前知识 (PK) 和记忆性能,分析了大脑激活和功能连接 (FC).
主要成果:
- 在正确检索的高 PK 项目中,前中间海马体 (amHPC) 激活率更高.
- 对于正确排斥的新高PK项目,后部海马体 (pHPC) 和vmPFC激活率更高.
- 在正确的排斥过程中,vmPFC和特定的海马/皮质区域之间的功能连接 (FC) 与PK水平有所不同.
结论:
- 涉及vmPFC,海马体子区域和认知控制区域的独特大脑网络被招募用于检索不同程度的先验知识 (PK) 的信息.
- 预先的知识在记忆检索过程中动态塑造神经活动和连接模式.
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